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Conversion of effector CD4(+) T cells to a CD8(+) MHC II-recognizing lineage

CD4(+) and CD8(+) T cells are dichotomous lineages in adaptive immunity. While conventionally viewed as distinct fates that are fixed after thymic development, accumulating evidence indicates that these two populations can exhibit significant lineage plasticity, particularly upon TCR-mediated activa...

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Bibliografski detalji
Izdano u:Cell Mol Immunol
Glavni autori: Robins, Elizabeth, Zheng, Ming, Ni, Qingshan, Liu, Siqi, Liang, Chen, Zhang, Baojun, Guo, Jian, Zhuang, Yuan, He, You-Wen, Zhu, Ping, Wan, Ying, Li, Qi-Jing
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7853072/
https://ncbi.nlm.nih.gov/pubmed/32066854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-019-0347-5
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