Artificial selection for host resistance to tumour growth and subsequent cancer cell adaptations: an evolutionary arms race

BACKGROUND: Cancer progression is governed by evolutionary dynamics in both the tumour population and its host. Since cancers die with the host, each new population of cancer cells must reinvent strategies to overcome the host’s heritable defences. In contrast, host species evolve defence strategies...

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Udgivet i:Br J Cancer
Main Authors: Ibrahim-Hashim, Arig, Luddy, Kimberly, Abrahams, Dominique, Enriquez-Navas, Pedro, Damgaci, Sultan, Yao, Jiqiang, Chen, Tingan, Bui, Marilyn M., Gillies, Robert J., O’Farrelly, Cliona, Richards, Christina L., Brown, Joel S., Gatenby, Robert A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852689/
https://ncbi.nlm.nih.gov/pubmed/33024265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-01110-1
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