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The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase

The methyltransferase SET domain–containing 2 (SETD2) was originally identified as Huntingtin (HTT) yeast partner B. However, a SETD2 function associated with the HTT scaffolding protein has not been elucidated, and no linkage between HTT and methylation has yet been uncovered. Here, we show that SE...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Adv
Prif Awduron: Seervai, Riyad N. H., Jangid, Rahul K., Karki, Menuka, Tripathi, Durga Nand, Jung, Sung Yun, Kearns, Sarah E., Verhey, Kristen J., Cianfrocco, Michael A., Millis, Bryan A., Tyska, Matthew J., Mason, Frank M., Rathmell, W. Kimryn, Park, In Young, Dere, Ruhee, Walker, Cheryl Lyn
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Association for the Advancement of Science 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852384/
https://ncbi.nlm.nih.gov/pubmed/33008892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb7854
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