The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase

The methyltransferase SET domain–containing 2 (SETD2) was originally identified as Huntingtin (HTT) yeast partner B. However, a SETD2 function associated with the HTT scaffolding protein has not been elucidated, and no linkage between HTT and methylation has yet been uncovered. Here, we show that SE...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Adv
Κύριοι συγγραφείς: Seervai, Riyad N. H., Jangid, Rahul K., Karki, Menuka, Tripathi, Durga Nand, Jung, Sung Yun, Kearns, Sarah E., Verhey, Kristen J., Cianfrocco, Michael A., Millis, Bryan A., Tyska, Matthew J., Mason, Frank M., Rathmell, W. Kimryn, Park, In Young, Dere, Ruhee, Walker, Cheryl Lyn
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Association for the Advancement of Science 2020
Θέματα:
Research Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852384/
https://ncbi.nlm.nih.gov/pubmed/33008892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb7854
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