The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase

The methyltransferase SET domain–containing 2 (SETD2) was originally identified as Huntingtin (HTT) yeast partner B. However, a SETD2 function associated with the HTT scaffolding protein has not been elucidated, and no linkage between HTT and methylation has yet been uncovered. Here, we show that SE...

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Detaylı Bibliyografya
Yayımlandı:Sci Adv
Asıl Yazarlar: Seervai, Riyad N. H., Jangid, Rahul K., Karki, Menuka, Tripathi, Durga Nand, Jung, Sung Yun, Kearns, Sarah E., Verhey, Kristen J., Cianfrocco, Michael A., Millis, Bryan A., Tyska, Matthew J., Mason, Frank M., Rathmell, W. Kimryn, Park, In Young, Dere, Ruhee, Walker, Cheryl Lyn
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Association for the Advancement of Science 2020
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852384/
https://ncbi.nlm.nih.gov/pubmed/33008892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb7854
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