The Huntingtin-interacting protein SETD2/HYPB is an actin lysine methyltransferase

The methyltransferase SET domain–containing 2 (SETD2) was originally identified as Huntingtin (HTT) yeast partner B. However, a SETD2 function associated with the HTT scaffolding protein has not been elucidated, and no linkage between HTT and methylation has yet been uncovered. Here, we show that SE...

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Publicado en:Sci Adv
Main Authors: Seervai, Riyad N. H., Jangid, Rahul K., Karki, Menuka, Tripathi, Durga Nand, Jung, Sung Yun, Kearns, Sarah E., Verhey, Kristen J., Cianfrocco, Michael A., Millis, Bryan A., Tyska, Matthew J., Mason, Frank M., Rathmell, W. Kimryn, Park, In Young, Dere, Ruhee, Walker, Cheryl Lyn
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2020
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852384/
https://ncbi.nlm.nih.gov/pubmed/33008892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb7854
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