Quantitative proteomic profiling of extracellular matrix and site-specific collagen post-translational modifications in an in vitro model of lung fibrosis

Lung fibrosis is characterized by excessive deposition of extracellular matrix (ECM), in particular collagens, by fibroblasts in the interstitium. Transforming growth factor-β1 (TGF-β1) alters the expression of many extracellular matrix (ECM) components produced by fibroblasts, but such changes in E...

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Veröffentlicht in:Matrix Biol Plus
Hauptverfasser: Merl-Pham, Juliane, Basak, Trayambak, Knüppel, Larissa, Ramanujam, Deepak, Athanason, Mark, Behr, Jürgen, Engelhardt, Stefan, Eickelberg, Oliver, Hauck, Stefanie M., Vanacore, Roberto, Staab-Weijnitz, Claudia A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852317/
https://ncbi.nlm.nih.gov/pubmed/33543004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mbplus.2019.04.002
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