CCN1 expression by fibroblasts is required for bleomycin-induced skin fibrosis

The microenvironment contributes to the excessive connective tissue deposition that characterizes fibrosis. Members of the CCN family of matricellular proteins are secreted by fibroblasts into the fibrotic microenvironment; however, the role of endogenous CCN1 in skin fibrosis is unknown. Mice harbo...

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Publicado en:Matrix Biol Plus
Autores principales: Quesnel, Katherine, Shi-wen, Xu, Hutchenreuther, James, Xiao, Yizhi, Liu, Shangxi, Peidl, Alexander, Naskar, Deboki, Siqueira, Walter L., O'Gorman, David B., Hinz, Boris, Stratton, Richard J., Leask, Andrew
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852207/
https://ncbi.nlm.nih.gov/pubmed/33543008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mbplus.2019.100009
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