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Negative allosteric modulators of metabotropic glutamate receptor 3 target the stem-like phenotype of glioblastoma
Glioblastoma is an invariably deadly disease. A subpopulation of glioma stem-like cells (GSCs) drives tumor progression and treatment resistance. Two recent studies demonstrated that neurons form oncogenic glutamatergic electrochemical synapses with post-synaptic GSCs. This led us to explore whether...
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| 出版年: | Mol Ther Oncolytics |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Gene & Cell Therapy
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7851500/ https://ncbi.nlm.nih.gov/pubmed/33575479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2020.12.009 |
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