Negative allosteric modulators of metabotropic glutamate receptor 3 target the stem-like phenotype of glioblastoma

Glioblastoma is an invariably deadly disease. A subpopulation of glioma stem-like cells (GSCs) drives tumor progression and treatment resistance. Two recent studies demonstrated that neurons form oncogenic glutamatergic electrochemical synapses with post-synaptic GSCs. This led us to explore whether...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Wirsching, Hans-Georg, Silginer, Manuela, Ventura, Elisa, Macnair, Will, Burghardt, Isabel, Claassen, Manfred, Gatti, Silvia, Wichmann, Jürgen, Riemer, Claus, Schneider, Hannah, Weller, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7851500/
https://ncbi.nlm.nih.gov/pubmed/33575479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2020.12.009
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados