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Allosteric Molecular Switches in Metabotropic Glutamate Receptors

Metabotropic glutamate receptors (mGlu) are class C G protein‐coupled receptors of eight subtypes that are omnipresently expressed in the central nervous system. mGlus have relevance in several psychiatric and neurological disorders, therefore they raise considerable interest as drug targets. Allost...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:ChemMedChem
Hauptverfasser: Orgován, Zoltán, Ferenczy, György G., Keserű, György M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7818470/
https://ncbi.nlm.nih.gov/pubmed/32686363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.202000444
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