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Interferon-stimulated GTPases in autoimmune and inflammatory diseases: promising role for the guanylate-binding protein (GBP) family

Human IFNs are secreted cytokines shown to stimulate the expression of over one thousand genes. These IFN-inducible genes primarily encode four major protein families, known as IFN-stimulated GTPases (ISGs), namely myxovirus-resistance proteins, guanylate-binding proteins (GBPs), p47 immunity-relate...

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Detalhes bibliográficos
Publicado no:Rheumatology (Oxford)
Main Authors: Haque, Mahamudul, Siegel, Ruby J, Fox, David A, Ahmed, Salahuddin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7850581/
https://ncbi.nlm.nih.gov/pubmed/33159795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/keaa609
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