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Identification of the Interferon-Inducible GTPase GBP1 as a Major Restriction Factor for Hepatitis E Virus

This study aims to gain deeper insight into hepatitis E virus (HEV)-induced innate immunity by characterizing the cross talk between the virus and the host factor guanylate-binding protein 1 (GBP1). We observe that the amount of GBP1 is elevated upon infection, although the number of transcripts is...

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Vydáno v:J Virol
Hlavní autoři: Glitscher, Mirco, Himmelsbach, Kiyoshi, Woytinek, Kathrin, Schollmeier, Anja, Johne, Reimar, Praefcke, Gerrit J. K., Hildt, Eberhard
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092694/
https://ncbi.nlm.nih.gov/pubmed/33472929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01564-20
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