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Immunity-related GTPase M (IRGM) Proteins Influence the Localization of Guanylate-binding Protein 2 (GBP2) by Modulating Macroautophagy

The immunity-related GTPases (IRGs) are a family of proteins induced by interferon-γ that play a crucial role in innate resistance to intracellular pathogens. The M subfamily of IRG proteins (IRGM) plays a profound role in this context, in part because of the ability of its members to regulate the l...

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Bibliografiske detaljer
Main Authors: Traver, Maria K., Henry, Stanley C., Cantillana, Viviana, Oliver, Tim, Hunn, Julia P., Howard, Jonathan C., Beer, Sandra, Pfeffer, Klaus, Coers, Jörn, Taylor, Gregory A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162407/
https://ncbi.nlm.nih.gov/pubmed/21757726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.251967
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