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Bioadhesive polymer/lipid hybrid nanoparticles as oral delivery system of raloxifene with enhancive intestinal retention and bioavailability

Raloxifene (RLX) is a second-generation selective estrogen receptor modulator used to treat osteoporosis in postmenopausal women. RLX fails to be developed into injectable dosage forms due to poor solubility. Although oral formulations are clinically available, the lower bioavailability (<2%) emb...

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Publicat a:Drug Deliv
Autors principals: Du, Xinhui, Gao, Na, Song, Xiaoyong
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7850345/
https://ncbi.nlm.nih.gov/pubmed/33501870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2021.1872742
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