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Bioadhesive polymer/lipid hybrid nanoparticles as oral delivery system of raloxifene with enhancive intestinal retention and bioavailability

Raloxifene (RLX) is a second-generation selective estrogen receptor modulator used to treat osteoporosis in postmenopausal women. RLX fails to be developed into injectable dosage forms due to poor solubility. Although oral formulations are clinically available, the lower bioavailability (<2%) emb...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Du, Xinhui, Gao, Na, Song, Xiaoyong
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7850345/
https://ncbi.nlm.nih.gov/pubmed/33501870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2021.1872742
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