Cholate-modified polymer-lipid hybrid nanoparticles for oral delivery of quercetin to potentiate the antileukemic effect

Background: Quercetin (QUE) shows a potential antileukemic activity, but possesses poor solubility and low bioavailability. Purpose: This article explored the bile salt transport pathway for oral deliver of QUE using cholate-modified polymer-lipid hybrid nanoparticles (cPLNs) aiming to enhance its a...

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Dettagli Bibliografici
Pubblicato in:Int J Nanomedicine
Autori principali: Yin, Juntao, Hou, Yantao, Song, Xiaoyong, Wang, Peiqing, Li, Yang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2019
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549487/
https://ncbi.nlm.nih.gov/pubmed/31213814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S210057
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