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Development and characterization of solid lipid nanoparticles for enhancement of oral bioavailability of Raloxifene

The objective of this study was to increase the oral bioavailability of Raloxifene having an absolute bioavailability only 2% due to extensive first pass hepatic metabolism by incorporating it in Solid Lipid Nanoparticles (SLNs). The optimized RSLNs prepared by Ultrasonic Emulsification and Low Temp...

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Detalhes bibliográficos
Main Authors: Patel, B. Divyakant, Modi, R. Valay, Thakkar, N. Alok, Patel, A. Arpita, Thakkar, P. Hetal
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467810/
https://ncbi.nlm.nih.gov/pubmed/23066188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0975-7406.94121
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