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Oral Bioavailability Enhancement of Raloxifene with Nanostructured Lipid Carriers

Raloxifene hydrochloride (RLX) shows poor bioavailability (<2%), high inter-patient variability and extensive gut metabolism (>90%). The objective of this study was to develop nanostructured lipid carriers (NLCs) for RLX to enhance its bioavailability. The NLC formulations were produced with g...

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Detalhes bibliográficos
Publicado no:Nanomaterials (Basel)
Main Authors: Murthy, Aditya, Rao Ravi, Punna, Kathuria, Himanshu, Malekar, Shrinivas
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7353254/
https://ncbi.nlm.nih.gov/pubmed/32486508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano10061085
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