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Oral bioavailability enhancement of agomelatine by loading into nanostructured lipid carriers: Peyer’s patch targeting approach

Agomelatine (AGM) is a new antidepressant drug with a novel mechanism of action and fewer side effects compared with older antidepressants. AGM is a melatonin receptor (MT1 and MT2) agonist and 5-hydroxytryptamine receptor (5-HT(2C)) antagonist. In the present study, the enhancement of the oral bioa...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Prajapati, Jagruti B, Verma, Sneha D, Patel, Amit A
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5863623/
https://ncbi.nlm.nih.gov/pubmed/29593392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S124703
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