Analysis of 1,25-Dihydroxyvitamin D(3) Genomic Action Reveals Calcium-Regulating and Calcium-Independent Effects in Mouse Intestine and Human Enteroids

Although vitamin D is critical for the function of the intestine, most studies have focused on the duodenum. We show that transgenic expression of the vitamin D receptor (VDR) only in the distal intestine of VDR null mice (KO/TG mice) results in the normalization of serum calcium and rescue of ricke...

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Publicado en:Mol Cell Biol
Autores principales: Li, Shanshan, De La Cruz, Jessica, Hutchens, Steven, Mukhopadhyay, Somshuvra, Criss, Zachary K., Aita, Rohit, Pellon-Cardenas, Oscar, Hur, Joseph, Soteropoulos, Patricia, Husain, Seema, Dhawan, Puneet, Verlinden, Lieve, Carmeliet, Geert, Fleet, James C., Shroyer, Noah F., Verzi, Michael P., Christakos, Sylvia
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849401/
https://ncbi.nlm.nih.gov/pubmed/33139494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00372-20
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