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Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects

1,25-Dihydroxvitamin D(3) [1,25(OH)(2)D(3)] is the hormonally active form of vitamin D. The genomic mechanism of 1,25(OH)(2)D(3) action involves the direct binding of the 1,25(OH)(2)D(3) activated vitamin D receptor/retinoic X receptor (VDR/RXR) heterodimeric complex to specific DNA sequences. Numer...

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Detalhes bibliográficos
Publicado no:Physiol Rev
Main Authors: Christakos, Sylvia, Dhawan, Puneet, Verstuyf, Annemieke, Verlinden, Lieve, Carmeliet, Geert
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4839493/
https://ncbi.nlm.nih.gov/pubmed/26681795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physrev.00014.2015
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