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Transgenic Expression of the Vitamin D Receptor Restricted to the Ileum, Cecum, and Colon of Vitamin D Receptor Knockout Mice Rescues Vitamin D Receptor−Dependent Rickets

Although the intestine plays the major role in 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] action on calcium homeostasis, the mechanisms involved remain incompletely understood. The established model of 1,25(OH)(2)D(3)-regulated intestinal calcium absorption postulates a critical role for the duode...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Dhawan, Puneet, Veldurthy, Vaishali, Yehia, Ghassan, Hsaio, Connie, Porta, Angela, Kim, Ki-in, Patel, Nishant, Lieben, Liesbet, Verlinden, Lieve, Carmeliet, Geert, Christakos, Sylvia
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695835/
https://ncbi.nlm.nih.gov/pubmed/28938396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00258
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