The Funnel: a Screening Technique for Identifying Optimal Two-Drug Combination Chemotherapy Regimens

The Mycobacterium tuberculosis drug discovery effort has generated a substantial number of new/repurposed drugs for therapy for this pathogen. The arrival of these drugs is welcome, but another layer of difficulty has emerged. Single agent therapy is insufficient for patients with late-stage tubercu...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Drusano, G. L., Kim, Sarah, Almoslem, Mohammed, Schmidt, Stephan, D’Argenio, D. Z., Myrick, Jenny, Duncanson, Brandon, Nole, Jocelyn, Brown, David, Peloquin, C. A., Neely, Michael, Yamada, Walter, Louie, Arnold
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2021
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848982/
https://ncbi.nlm.nih.gov/pubmed/33199386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02172-20
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