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Linezolid Kills Acid-Phase and Nonreplicative-Persister-Phase Mycobacterium tuberculosis in a Hollow-Fiber Infection Model

The therapy for treatment of Mycobacterium tuberculosis infections is long and arduous. It has been hypothesized that the therapy duration is driven primarily by populations of organisms in different metabolic states that replicate slowly or not at all (acid-phase and nonreplicative-persister [NRP]-...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Drusano, G. L., Myrick, Jenny, Maynard, Michael, Nole, Jocelyn, Duncanson, Brandon, Brown, David, Schmidt, Stephan, Neely, Michael, Scanga, C. A., Peloquin, Charles, Louie, Arnold
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105790/
https://ncbi.nlm.nih.gov/pubmed/29866864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00221-18
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