Hydrogen sulfide is neuroprotective in Alzheimer’s disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation

Alzheimer’s disease (AD), the most common cause of dementia and neurodegeneration in the elderly, is characterized by deterioration of memory and executive and motor functions. Neuropathologic hallmarks of AD include neurofibrillary tangles (NFTs), paired helical filaments, and amyloid plaques. Muta...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Giovinazzo, Daniel, Bursac, Biljana, Sbodio, Juan I., Nalluru, Sumedha, Vignane, Thibaut, Snowman, Adele M., Albacarys, Lauren M., Sedlak, Thomas W., Torregrossa, Roberta, Whiteman, Matthew, Filipovic, Milos R., Snyder, Solomon H., Paul, Bindu D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2021
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848711/
https://ncbi.nlm.nih.gov/pubmed/33431651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2017225118
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