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Structural effects of stabilization and complexation of a zinc-deficient superoxide dismutase

The activity of the erythrocyte Cu(2),Zn(2)-superoxide dismutase (SOD1) is altered in Alzheimer's disease (AD) patients. These patients, compared to healthy subjects, exhibit low plasmatic zinc (Zn) levels in the presence of high plasmatic levels of copper (Cu). SOD1 is an antioxidant enzyme ch...

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Publicat a:Heliyon
Autors principals: Manieri, Tania M., Sensi, Stefano L., Squitti, Rosanna, Cerchiaro, Giselle
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848637/
https://ncbi.nlm.nih.gov/pubmed/33553758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2021.e06100
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