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Discrete TrkB-expressing neurons of the dorsomedial hypothalamus regulate feeding and thermogenesis

Mutations in the TrkB neurotrophin receptor lead to profound obesity in humans, and expression of TrkB in the dorsomedial hypothalamus (DMH) is critical for maintaining energy homeostasis. However, the functional implications of TrkB-fexpressing neurons in the DMH (DMH(TrkB)) on energy expenditure a...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Houtz, Jessica, Liao, Guey-Ying, An, Juan Ji, Xu, Baoji
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848633/
https://ncbi.nlm.nih.gov/pubmed/33468645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2017218118
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