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Discrete TrkB-expressing neurons of the dorsomedial hypothalamus regulate feeding and thermogenesis

Mutations in the TrkB neurotrophin receptor lead to profound obesity in humans, and expression of TrkB in the dorsomedial hypothalamus (DMH) is critical for maintaining energy homeostasis. However, the functional implications of TrkB-fexpressing neurons in the DMH (DMH(TrkB)) on energy expenditure a...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Houtz, Jessica, Liao, Guey-Ying, An, Juan Ji, Xu, Baoji
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848633/
https://ncbi.nlm.nih.gov/pubmed/33468645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2017218118
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