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Metabolite Profiling of Dihydroartemisinin in Blood of Plasmodium-Infected and Healthy Mice Using UPLC-Q-TOF-MS(E)

Dihydroartemisinin (DHA) and its’ derivatives have been employed as the most powerful first-line drugs for malarial treatment for several decades. The metabolism of DHA has not been studied clearly. Previous reports were focused on the pharmacokinetics procedure of DHA in healthy rats. The metabolit...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Zhao, Yifan, Sun, Peng, Ma, Yue, Chang, Xiaoqiang, Chen, Xingyu, Ji, Xin, Bai, Yue, Zhang, Dong, Yang, Lan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7848114/
https://ncbi.nlm.nih.gov/pubmed/33536920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.614159
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