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Evaluation of Microbial Transformation of 10-deoxoartemisinin by UPLC-ESI-Q-TOF-MS(E)

10-deoxoartemisinin is a semisynthetic derivative of artemisinin that lacks a lactone carbonyl group at the 10-position, and has stronger antimalarial properties than artemisinin. However, 10-deoxoartemisinin has limited utility as a therapeutic agent because of its low solubility and bioavailabilit...

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Podrobná bibliografie
Vydáno v:Molecules
Hlavní autoři: Bai, Yue, Zhang, Dong, Sun, Peng, Zhao, Yifan, Chang, Xiaoqiang, Ma, Yue, Yang, Lan
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864820/
https://ncbi.nlm.nih.gov/pubmed/31661766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24213874
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