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SAM68 promotes tumorigenesis in lung adenocarcinoma by regulating metabolic conversion via PKM alternative splicing

Background: A metabolic “switch” from oxidative phosphorylation to glycolysis provides tumor cells with energy and biosynthetic substrates, thereby promoting tumorigenesis and malignant progression. However, the mechanisms controlling this metabolic switch in tumors is not entirely clear. Methods: C...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Zhu, Song, Chen, Weiping, Wang, Jizhong, Qi, Ling, Pan, Huilin, Feng, Zhengfu, Tian, Dongbo
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7847678/
https://ncbi.nlm.nih.gov/pubmed/33537092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.51360
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