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Geranylgeranylacetone ameliorated ischemia/reperfusion induced-blood brain barrier breakdown through HSP70-dependent anti-apoptosis effect

Background: Geranylgeranylacetone (GGA) has been recently reported to be centrally active after oral administration and protect against ischemic brain injury. This study was aimed to investigate the underlying mechanism of the protective effect of GGA. Methods: In this study, transient middle cerebr...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Li, Fazhao, Gong, Xiyu, Yang, Binbin
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7847529/
https://ncbi.nlm.nih.gov/pubmed/33527011
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