Geranylgeranylacetone attenuates cerebral ischemia–reperfusion injury in rats through the augmentation of HSP 27 phosphorylation: a preliminary study

BACKGROUND: We previously reported that heat shock protein 27 (HSP27) phosphorylation plays an important role in the activation of glucose-6-phosphate dehydrogenase (G6PD), resulting in the upregulation of the pentose phosphate pathway and antioxidant effects against cerebral ischemia–reperfusion in...

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Udgivet i:BMC Neurosci
Main Authors: Matsuo, Kazuya, Hosoda, Kohkichi, Tanaka, Jun, Yamamoto, Yusuke, Imahori, Taichiro, Nakai, Tomoaki, Irino, Yasuhiro, Shinohara, Masakazu, Sasayama, Takashi, Kohmura, Eiji
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7869466/
https://ncbi.nlm.nih.gov/pubmed/33557752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-021-00614-7
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