A new generation needle- and adjuvant-free trivalent plague vaccine utilizing adenovirus-5 nanoparticle platform

A plague vaccine with a fusion cassette of YscF, F1, and LcrV encoding genes in an adenovirus-5 vector (rAd5-YFV) is evaluated for efficacy and immune responses in mice. Two doses of the vaccine provides 100% protection when administered intranasally against challenge with Yersinia pestis CO92 or it...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:NPJ Vaccines
Huvudupphovsmän: Kilgore, Paul B., Sha, Jian, Andersson, Jourdan A., Motin, Vladimir L., Chopra, Ashok K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2021
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846801/
https://ncbi.nlm.nih.gov/pubmed/33514747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-020-00275-3
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk