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Backbone-independent NMR resonance assignments of methyl probes in large proteins
Methyl-specific isotope labeling is a powerful tool to study the structure, dynamics and interactions of large proteins and protein complexes by solution-state NMR. However, widespread applications of this methodology have been limited by challenges in obtaining confident resonance assignments. Here...
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| 發表在: | Nat Commun |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7846771/ https://ncbi.nlm.nih.gov/pubmed/33514730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-20984-0 |
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