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Automatic structure-based NMR methyl resonance assignment in large proteins
Isotopically labeled methyl groups provide NMR probes in large, otherwise deuterated proteins. However, the resonance assignment constitutes a bottleneck for broader applicability of methyl-based NMR. Here, we present the automated MethylFLYA method for the assignment of methyl groups that is based...
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| Published in: | Nat Commun |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group UK
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6820720/ https://ncbi.nlm.nih.gov/pubmed/31664028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12837-8 |
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