Rosmarinic acid suppresses tau phosphorylation and cognitive decline by downregulating the JNK signaling pathway

Rosmarinic acid (RA), a polyphenol found in Lamiaceae herbs, is a candidate of preventive ingredients against Alzheimer’s disease (AD) as it potently suppresses the aggregation of amyloid β (Aβ); however, the effect of RA on tau phosphorylation and cognitive dysfunction remains unclear. The present...

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Udgivet i:NPJ Sci Food
Main Authors: Yamamoto, So, Kayama, Tomoko, Noguchi-Shinohara, Moeko, Hamaguchi, Tsuyoshi, Yamada, Masahito, Abe, Keiko, Kobayashi, Shoko
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7846760/
https://ncbi.nlm.nih.gov/pubmed/33514742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41538-021-00084-5
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