Safety and efficacy of Melissa officinalis extract containing rosmarinic acid in the prevention of Alzheimer’s disease progression

We conducted a randomized placebo-controlled double-blind 24-week trial using Melissa officinalis (M. officinalis) extract richly containing rosmarinic acid (RA) on patients with mild dementia due to Alzheimer’s disease (AD) with the aim to examine the safety and tolerability (primary endpoint) of R...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Noguchi-Shinohara, Moeko, Ono, Kenjiro, Hamaguchi, Tsuyoshi, Nagai, Toshitada, Kobayashi, Shoko, Komatsu, Junji, Samuraki-Yokohama, Miharu, Iwasa, Kazuo, Yokoyama, Kunihiko, Nakamura, Hiroyuki, Yamada, Masahito
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596544/
https://ncbi.nlm.nih.gov/pubmed/33122694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73729-2
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