Safety and efficacy of Melissa officinalis extract containing rosmarinic acid in the prevention of Alzheimer’s disease progression

We conducted a randomized placebo-controlled double-blind 24-week trial using Melissa officinalis (M. officinalis) extract richly containing rosmarinic acid (RA) on patients with mild dementia due to Alzheimer’s disease (AD) with the aim to examine the safety and tolerability (primary endpoint) of R...

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Vydáno v:Sci Rep
Hlavní autoři: Noguchi-Shinohara, Moeko, Ono, Kenjiro, Hamaguchi, Tsuyoshi, Nagai, Toshitada, Kobayashi, Shoko, Komatsu, Junji, Samuraki-Yokohama, Miharu, Iwasa, Kazuo, Yokoyama, Kunihiko, Nakamura, Hiroyuki, Yamada, Masahito
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596544/
https://ncbi.nlm.nih.gov/pubmed/33122694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73729-2
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