Safety and efficacy of Melissa officinalis extract containing rosmarinic acid in the prevention of Alzheimer’s disease progression

We conducted a randomized placebo-controlled double-blind 24-week trial using Melissa officinalis (M. officinalis) extract richly containing rosmarinic acid (RA) on patients with mild dementia due to Alzheimer’s disease (AD) with the aim to examine the safety and tolerability (primary endpoint) of R...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Noguchi-Shinohara, Moeko, Ono, Kenjiro, Hamaguchi, Tsuyoshi, Nagai, Toshitada, Kobayashi, Shoko, Komatsu, Junji, Samuraki-Yokohama, Miharu, Iwasa, Kazuo, Yokoyama, Kunihiko, Nakamura, Hiroyuki, Yamada, Masahito
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596544/
https://ncbi.nlm.nih.gov/pubmed/33122694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73729-2
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