Rosmarinic acid suppresses Alzheimer’s disease development by reducing amyloid β aggregation by increasing monoamine secretion

A new mechanism is revealed by which a polyphenol, rosmarinic acid (RA), suppresses amyloid β (Aβ) accumulation in mice. Here we examined the brains of mice (Alzheimer’s disease model) using DNA microarray analysis and revealed that the dopamine (DA)-signaling pathway was enhanced in the group fed R...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Hase, Tomoki, Shishido, Syun, Yamamoto, So, Yamashita, Rei, Nukima, Haruka, Taira, Shu, Toyoda, Tsudoi, Abe, Keiko, Hamaguchi, Tsuyoshi, Ono, Kenjiro, Noguchi-Shinohara, Moeko, Yamada, Masahito, Kobayashi, Shoko
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581955/
https://ncbi.nlm.nih.gov/pubmed/31213631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45168-1
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky