טוען...
Genome-wide prediction of topoisomerase IIβ binding by architectural factors and chromatin accessibility
DNA topoisomerase II-β (TOP2B) is fundamental to remove topological problems linked to DNA metabolism and 3D chromatin architecture, but its cut-and-reseal catalytic mechanism can accidentally cause DNA double-strand breaks (DSBs) that can seriously compromise genome integrity. Understanding the fac...
שמור ב:
| הוצא לאור ב: | PLoS Comput Biol |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2021
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7845959/ https://ncbi.nlm.nih.gov/pubmed/33465072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007814 |
| תגים: |
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