Dichloroacetate and Pyruvate Metabolism: Pyruvate Dehydrogenase Kinases as Targets Worth Investigating for Effective Therapy of Toxoplasmosis

Toxoplasmosis, a protozoan infection caused by Toxoplasma gondii, is estimated to affect around 2.5 billion people worldwide. Nevertheless, the side effects of drugs combined with the long period of therapy usually result in discontinuation of the treatment. New therapies should be developed by expl...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Ferrarini, Mariana Galvão, Nisimura, Lindice Mitie, Girard, Richard Marcel Bruno Moreira, Alencar, Mayke Bezerra, Fragoso, Mariana Sayuri Ishikawa, Araújo-Silva, Carlla Assis, Veiga, Alan de Almeida, Abud, Ana Paula Ressetti, Nardelli, Sheila Cristina, Vommaro, Rossiane C., Silber, Ariel Mariano, France-Sagot, Marie, Ávila, Andréa Rodrigues
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7845590/
https://ncbi.nlm.nih.gov/pubmed/33408226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.01002-20
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