Flucloxacillin bone and soft tissue concentrations assessed by microdialysis in pigs after intravenous and oral administration

AIMS: Flucloxacillin is commonly administered intravenously for perioperative antimicrobial prophylaxis, while oral administration is typical for prophylaxis following smaller traumatic wounds. We assessed the time, for which the free flucloxacillin concentration was maintained above the minimum inh...

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Veröffentlicht in:Bone Joint Res
Hauptverfasser: Bendtsen, Mathias A. F., Bue, Mats, Hanberg, Pelle, Slater, Josefine, Thomassen, Maja B., Hansen, Jakob, Søballe, Kjeld, Öbrink-Hansen, Kristina, Stilling, Maiken
Format: Artigo
Sprache:Inglês
Veröffentlicht: The British Editorial Society of Bone & Joint Surgery 2021
Schlagworte:
Infection
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7845458/
https://ncbi.nlm.nih.gov/pubmed/33448872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1302/2046-3758.101.BJR-2020-0250.R1
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