Flucloxacillin bone and soft tissue concentrations assessed by microdialysis in pigs after intravenous and oral administration

AIMS: Flucloxacillin is commonly administered intravenously for perioperative antimicrobial prophylaxis, while oral administration is typical for prophylaxis following smaller traumatic wounds. We assessed the time, for which the free flucloxacillin concentration was maintained above the minimum inh...

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Detalhes bibliográficos
Publicado no:Bone Joint Res
Main Authors: Bendtsen, Mathias A. F., Bue, Mats, Hanberg, Pelle, Slater, Josefine, Thomassen, Maja B., Hansen, Jakob, Søballe, Kjeld, Öbrink-Hansen, Kristina, Stilling, Maiken
Formato: Artigo
Idioma:Inglês
Publicado em: The British Editorial Society of Bone & Joint Surgery 2021
Assuntos:
Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7845458/
https://ncbi.nlm.nih.gov/pubmed/33448872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1302/2046-3758.101.BJR-2020-0250.R1
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