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Flucloxacillin bone and soft tissue concentrations assessed by microdialysis in pigs after intravenous and oral administration

AIMS: Flucloxacillin is commonly administered intravenously for perioperative antimicrobial prophylaxis, while oral administration is typical for prophylaxis following smaller traumatic wounds. We assessed the time, for which the free flucloxacillin concentration was maintained above the minimum inh...

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Détails bibliographiques
Publié dans:Bone Joint Res
Auteurs principaux: Bendtsen, Mathias A. F., Bue, Mats, Hanberg, Pelle, Slater, Josefine, Thomassen, Maja B., Hansen, Jakob, Søballe, Kjeld, Öbrink-Hansen, Kristina, Stilling, Maiken
Format: Artigo
Langue:Inglês
Publié: The British Editorial Society of Bone & Joint Surgery 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7845458/
https://ncbi.nlm.nih.gov/pubmed/33448872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1302/2046-3758.101.BJR-2020-0250.R1
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