Tumor-intrinsic and -extrinsic determinants of response to blinatumomab in adults with B-ALL

Blinatumomab, a bispecific antibody that directs CD3(+) T cells to CD19(+) tumor cells, shows variable efficacy in B-progenitor acute lymphoblastic leukemia (B-ALL). To determine tumor-intrinsic and -extrinsic determinants of response, we studied 44 adults with relapsed or refractory B-ALL (includin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Blood
Main Authors: Zhao, Yaqi, Aldoss, Ibrahim, Qu, Chunxu, Crawford, Jeremy Chase, Gu, Zhaohui, Allen, Emma K., Zamora, Anthony E., Alexander, Thomas B., Wang, Jeremy, Goto, Hiroaki, Imamura, Toshihiko, Akahane, Koshi, Marcucci, Guido, Stein, Anthony S., Bhatia, Ravi, Thomas, Paul G., Forman, Stephen J., Mullighan, Charles G., Roberts, Kathryn G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2021
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7845009/
https://ncbi.nlm.nih.gov/pubmed/32881995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020006287
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados