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Selected before selection: A case for inherent antigen bias in the T cell receptor repertoire

T cell receptor recombination is frequently described as a random or semi-random process that belies the now well-established principle that recombination is extremely biased towards the generation of particular receptor chains. Here we describe the experimental and theoretical work arising from new...

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Detalhes bibliográficos
Publicado no:Curr Opin Syst Biol
Main Authors: Thomas, Paul G., Crawford, Jeremy Chase
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7323506/
https://ncbi.nlm.nih.gov/pubmed/32601606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coisb.2019.10.007
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