Quantifiable predictive features define epitope specific T cell receptor repertoires

T cells are defined by a heterodimeric surface receptor (the T cell receptor or TCR) that mediates recognition of pathogen-associated epitopes via interactions with peptide-major histocompatibility complexes (pMHC). TCRs are generated by genomic rearrangements of the germline TCR locus, a process te...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nature
Päätekijät: Dash, Pradyot, Fiore-Gartland, Andrew J., Hertz, Tomer, Wang, George C., Sharma, Shalini, Souquette, Aisha, Crawford, Jeremy Chase, Clemens, E. Bridie, Nguyen, Thi H. O., Kedzierska, Katherine, La Gruta, Nicole L., Bradley, Philip, Thomas, Paul G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5616171/
https://ncbi.nlm.nih.gov/pubmed/28636592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22383
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