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miR-135a Confers Resistance to Gefitinib in Non-Small Cell Lung Cancer Cells by Upregulation of RAC1

The EGFR tyrosine kinase inhibitor gefitinib is used in therapy for non-small cell lung cancer (NSCLC). However, the therapeutic efficacy of gefitinib is known to be impeded by mutations of EGFR. The aim of the present study was to reveal the role of miR-135a in gefitinib resistance of NSCLC cells....

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Foilsithe in:Oncol Res
Main Authors: Zhang, Tingting, Wang, Ning
Formáid: Artigo
Teanga:Inglês
Foilsithe: Cognizant Communication Corporation 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844633/
https://ncbi.nlm.nih.gov/pubmed/29386087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096504018X15166204902353
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