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miR-762 activation confers acquired resistance to gefitinib in non-small cell lung cancer

BACKGROUND: Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) (e.g. gefitinib) currently remain the first-line treatment for patients with advanced non-small-cell lung cancer (NSCLC) with activating EGFR mutation. However, acquired resistance to gefitinib, which occurs freque...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Ge, Peng, Cao, Lei, Chen, Xin, Jing, Ruijun, Yue, Wanxia
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6905032/
https://ncbi.nlm.nih.gov/pubmed/31823748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6416-4
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