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miR-135a Confers Resistance to Gefitinib in Non-Small Cell Lung Cancer Cells by Upregulation of RAC1

The EGFR tyrosine kinase inhibitor gefitinib is used in therapy for non-small cell lung cancer (NSCLC). However, the therapeutic efficacy of gefitinib is known to be impeded by mutations of EGFR. The aim of the present study was to reveal the role of miR-135a in gefitinib resistance of NSCLC cells....

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Vydáno v:Oncol Res
Hlavní autoři: Zhang, Tingting, Wang, Ning
Médium: Artigo
Jazyk:Inglês
Vydáno: Cognizant Communication Corporation 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7844633/
https://ncbi.nlm.nih.gov/pubmed/29386087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096504018X15166204902353
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